Template:Cell Cycle Exercises

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===Modeling the Cell Cycle Exercise=== Work in groups of 3. Work with people from different discipline. The goal of the lab is to become familiar with the software and the process of constructing a model. ====A. Draw flow diagrams or concept map for the statements provided below.==== 1.Create a concept map of the following: * inactive MPF becomes active MPF * Active MPF becomes inactive MPF 2.Concept map the following: * Cyclin is synthesized and degraded * Cyclin stimulates inactive MPF to become active MPF ====B. Create the same concept maps in Stella.==== [http://webster.cs.uga.edu/%7Ecs1210/Lectures/Stella/Intro.html Intro to Stella Controls] How do we create a reaction in Stella? What are the factors in a reaction? ====C. What goes in the boxes? Reaction rates [[Exercise rationale]]==== 1. Consider all reactions to be linear and based on the law of [http://eot.bu.edu/ccb/Kinetics/RateLaws/MassAction.htm mass action] (rate constant x substrate). 2. Use two of following set of rate constants in the rate equation: 0.05, 0.1, 1.0 3. Select initial concentration values for cyclin and MPF stocks in a range from 0.1 to 1. Choose at least three values to examine. Write a notes (report) containing the following: 1. Describe the characteristics of one set of simulation results. 2. Describe briefly why you think you obtained the results you did? 3. What questions came up if any? Exercise version 7/30/07 For additional work, try entering additional kinetic reactions and paramter values from the [[Media:GoldbeterParamterValues.pdf| table]]

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