http://raquell.us/ccb/index.php?action=history&feed=atom&title=Template%3ACell_Cycle_Exercise_2 2026-04-12T12:33:24Z Revision history for this page on the wiki MediaWiki 1.16.0 http://raquell.us/ccb/index.php?title=Template:Cell_Cycle_Exercise_2&diff=142&oldid=prev 2007-05-02T22:46:07Z

<p>New page: ===Exercise 2: Playing with Existing Models=== Exercise using an existing model of Goldbeter in Stella Demo Purpose: To become oriented with the model and the software. This exercise was ...</p> <p><b>New page</b></p><div>===Exercise 2: Playing with Existing Models===<br /> Exercise using an existing model of Goldbeter in Stella Demo<br /> <br /> Purpose: To become oriented with the model and the software. This exercise was designed to work with Stella Demo or Player.<br /> <br /> Click through the levels of the model (interface to model and equations) using the up and down arrows in the top left corner.<br /> <br /> The values in the right hand column of the tables “Variable values” and “Vmax of other reactions” can be changed by typing directly into the cell.<br /> <br /> Exploration<br /> <br /> 1. Run the simulation with the slider for “Vmax Cyclin degradation” to the far left (0.02).<br /> <br /> What results do you see in the graphs?<br /> <br /> How are the reaction velocities changed?<br /> <br /> Does it matter if you change the initial values of the variables?<br /> <br /> <br /> 2. Re-run the simulation with the slider for “Vmax Cyclin degradation” placed to the far right (0.6)?<br /> <br /> What results do you see?<br /> <br /> How are the reaction velocities changed?<br /> <br /> Does it matter if you change the initial values of the variables?<br /> <br /> At what ~value of Vmax cyclin degradation are oscillations lost?<br /> <br /> <br /> Note: Non-degradable cyclin is one of the experimental tools used to characterize cell cycle dynamics.</div>

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